Lactosylated liposomes for targeted delivery of doxorubicin to hepatocellular carcinoma

BACKGROUND: N-lactosyl-dioleoylphosphatidylethanolamine (Lac-DOPE) was synthesized and evaluated as a liver-specific targeting ligand via asialoglycoprotein receptors for liposomal delivery of doxorubicin. METHODS: Lactosylated liposomes encapsulating calcein (Lac-L-calcein) or doxorubicin (Lac-L-DO...

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Autors principals: Zhou, Xiaoju, Zhang, Mengzi, Yung, Bryant, Li, Hong, Zhou, Chenguang, Lee, L James, Lee, Robert J
Format: Artigo
Idioma:Inglês
Publicat: Dove Medical Press 2012
Matèries:
Original Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3476751/
https://ncbi.nlm.nih.gov/pubmed/23093902
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S33965
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