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Pyridine analogs inhibit the glucosyltransferase of Streptococcus mutans.

Soluble glucan synthesis catalyzed by dextransucrase preparations from Streptococcus mutans 6715 were inhibited by pyridoxal-5-phosphate and several other pyridine analogs, including pyridoxine, pyridoxamine, pyridoxamine-5-phosphate, pyridoxal, and 4-pyridoxic acid. Pyridine and pyridine-4-carboxal...

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Bibliographic Details
Main Authors: Thaniyavarn, S, Taylor, K G, Singh, S, Doyle, R J
Format: Artigo
Language:Inglês
Published: 1982
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC347654/
https://ncbi.nlm.nih.gov/pubmed/6215355
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