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Concerted action of the PHD, chromo and motor domains regulates the human chromatin remodelling ATPase CHD4

CHD4, the core subunit of the Nucleosome Remodelling and Deacetylase (NuRD) complex, is a chromatin remodelling ATPase that, in addition to a helicase domain, harbors tandem plant homeo finger and chromo domains. By using a panel of domain constructs we dissect their roles and demonstrate that DNA b...

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Détails bibliographiques
Auteurs principaux: Morra, Rosa, Lee, Benjamin M., Shaw, Heather, Tuma, Roman, Mancini, Erika J.
Format: Artigo
Langue:Inglês
Publié: Elsevier Science B.V 2012
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3476528/
https://ncbi.nlm.nih.gov/pubmed/22749909
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.febslet.2012.06.017
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