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Effects of the Delta Opioid Receptor Agonist SNC80 on Pain-Related Depression of Intracranial Self-Stimulation (ICSS) in Rats

The delta opioid receptor agonist SNC80 produces both antinociceptive and antidepressant effects in rodents. This profile suggests that SNC80 may also reverse prodepressant effects of pain. Accordingly, this study compared SNC80 effects in complementary assays of pain-stimulated and pain-depressed b...

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Bibliographic Details
Main Authors: Negus, S. Stevens, Rosenberg, Marisa B., Altarifi, Ahmad A., O’Connell, Robert H., Folk, John E., Rice, Kenner C.
Format: Artigo
Language:Inglês
Published: 2012
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3476476/
https://ncbi.nlm.nih.gov/pubmed/22424913
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jpain.2011.12.003
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