Cytosolic re-localization and optimization of valine synthesis and catabolism enables inseased isobutanol production with the yeast Saccharomyces cerevisiae

BACKGROUND: The branched chain alcohol isobutanol exhibits superior physicochemical properties as an alternative biofuel. The yeast Saccharomyces cerevisiae naturally produces low amounts of isobutanol as a by-product during fermentations, resulting from the catabolism of valine. As S. cerevisiae is...

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Autori principali: Brat, Dawid, Weber, Christian, Lorenzen, Wolfram, Bode, Helge B, Boles, Eckhard
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2012
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3476451/
https://ncbi.nlm.nih.gov/pubmed/22954227
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1754-6834-5-65
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