Computed Tomography-guided Time-domain Diffuse Fluorescence Tomography in Small Animals for Localization of Cancer Biomarkers

Small animal fluorescence molecular imaging (FMI) can be a powerful tool for preclinical drug discovery and development studies(1). However, light absorption by tissue chromophores (e.g., hemoglobin, water, lipids, melanin) typically limits optical signal propagation through thicknesses larger than...

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Main Authors: Tichauer, Kenneth M., Holt, Robert W., Samkoe, Kimberley S., El-Ghussein, Fadi, Gunn, Jason R., Jermyn, Michael, Dehghani, Hamid, Leblond, Frederic, Pogue, Brian W.
Formato: Artigo
Idioma:Inglês
Publicado: MyJove Corporation 2012
Assuntos:
Cancer Biology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3476420/
https://ncbi.nlm.nih.gov/pubmed/22847515
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/4050
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