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Facilitating Drug Discovery: An Automated High-content Inflammation Assay in Zebrafish

Zebrafish larvae are particularly amenable to whole animal small molecule screens(1,2) due to their small size and relative ease of manipulation and observation, as well as the fact that compounds can simply be added to the bathing water and are readily absorbed when administered in a <1% DMSO so...

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Detalhes bibliográficos
Main Authors: Wittmann, Christine, Reischl, Markus, Shah, Asmi H., Mikut, Ralf, Liebel, Urban, Grabher, Clemens
Formato: Artigo
Idioma:Inglês
Publicado em: MyJove Corporation 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3476412/
https://ncbi.nlm.nih.gov/pubmed/22825322
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/4203
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