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Characterization of the Mechanism and Magnitude of Cytoglobin-mediated Nitrite Reduction and Nitric Oxide Generation under Anaerobic Conditions

Cytoglobin (Cygb) is a recently discovered cytoplasmic heme-binding globin. Although multiple hemeproteins have been reported to function as nitrite reductases in mammalian cells, it is unknown whether Cygb can also reduce nitrite to nitric oxide (NO). The mechanism, magnitude, and quantitative impo...

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Detalhes bibliográficos
Main Authors: Li, Haitao, Hemann, Craig, Abdelghany, Tamer M., El-Mahdy, Mohamed A., Zweier, Jay L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3476328/
https://ncbi.nlm.nih.gov/pubmed/22896706
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.342378
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