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Resolving the Negative Potential Side (n-side) Water-accessible Proton Pathway of F-type ATP Synthase by Molecular Dynamics Simulations

The rotation of F(1)F(o)-ATP synthase is powered by the proton motive force across the energy-transducing membrane. The protein complex functions like a turbine; the proton flow drives the rotation of the c-ring of the transmembrane F(o) domain, which is coupled to the ATP-producing F(1) domain. The...

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Hlavní autoři: Gohlke, Holger, Schlieper, Daniel, Groth, Georg
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3476320/
https://ncbi.nlm.nih.gov/pubmed/22942277
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.398396
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