Identification of HEXIM1 as a Positive Regulator of p53

Hexamethylene bisacetamide-inducible protein 1 (HEXIM1) is best known as the inhibitor of positive transcription elongation factor b (P-TEFb), which regulates the transcription elongation of RNA polymerase II and controls 60–70% of mRNA synthesis. Our previous studies show that HEXIM1 interacts with...

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Main Authors: Lew, Qiao Jing, Chia, Yi Ling, Chu, Kai Ling, Lam, Yuen Ting, Gurumurthy, Meera, Xu, Shengli, Lam, Kong Peng, Cheong, Nge, Chao, Sheng-Hao
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2012
Teme:
Gene Regulation
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3476310/
https://ncbi.nlm.nih.gov/pubmed/22948151
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.374157
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