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Crystal Structures of a CTXφ pIII Domain Unbound and in Complex with a Vibrio cholerae TolA Domain Reveal Novel Interaction Interfaces

Vibrio cholerae colonize the small intestine where they secrete cholera toxin, an ADP-ribosylating enzyme that is responsible for the voluminous diarrhea characteristic of cholera disease. The genes encoding cholera toxin are located on the genome of the filamentous bacteriophage, CTXφ, that integra...

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Main Authors: Ford, Christopher G., Kolappan, Subramaniapillai, Phan, Hanh T. H., Waldor, Matthew K., Winther-Larsen, Hanne C., Craig, Lisa
格式: Artigo
語言:Inglês
出版: American Society for Biochemistry and Molecular Biology 2012
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3476293/
https://ncbi.nlm.nih.gov/pubmed/22942280
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.403386
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