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IFN-γ-independent intraocular tumor rejection is mediated by a macrophage-dependent process that leaves the eye intact

Intraocular tumors reside in an immune-privileged site, yet in certain circumstances, they can undergo immune rejection. Ocular tumor rejection can follow one of two pathways. One pathway is CD4(+) T cell-dependent and culminates in ischemic necrosis of the tumor and phthisis (atrophy) of the eye. A...

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Detalles Bibliográficos
Main Authors: Coursey, Terry G., Chen, Peter W., Niederkorn, Jerry Y.
Formato: Artigo
Idioma:Inglês
Publicado: Society for Leukocyte Biology 2012
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3476238/
https://ncbi.nlm.nih.gov/pubmed/22693246
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.0312122
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