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Increased activity of serotonin uptake in platelets in medication overuse headache following regular intake of analgesics and triptans

We investigated the effect of chronic administration of different pain medications on the activity of the serotonin transporter (SERT) in patients with medication overuse headache (MOH). We measured the kinetic of platelet 5-HT uptake (maximal velocity, V(max) and the Michaelis–Menten constant, K(m)...

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Detalhes bibliográficos
Main Authors: Ayzenberg, Ilya, Oberman, Mark, Leineweber, Kirsten, Franke, Leonora, Yoon, Min-Suk, Diener, Hans-Christoph, Katsarava, Zaza
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Milan 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3476187/
https://ncbi.nlm.nih.gov/pubmed/18330504
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10194-008-0019-9
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