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Rationalizing Structure and Target Relationships between Current Drugs

A recent analysis of structure and target relationships between current drugs and bioactive compounds has revealed that only a small fraction of drugs that are active against the same or overlapping targets are involved in substructure relationships and/or share the same topology. By contrast, struc...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Hu, Ye, Bajorath, Jürgen
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: Springer US 2012
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3475854/
https://ncbi.nlm.nih.gov/pubmed/22826035
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12248-012-9392-z
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