Pharmacokinetics and Tissue Disposition of Lenalidomide in Mice

Lenalidomide is a synthetic derivative of thalidomide exhibiting multiple immunomodulatory activities beneficial in the treatment of several hematological malignancies. Murine pharmacokinetic characterization necessary for translational and further preclinical investigations has not been published....

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Main Authors: Rozewski, Darlene M., Herman, Sarah E. M., Towns, William H., Mahoney, Emilia, Stefanovski, Matthew R., Shin, Jungook D., Yang, Xiaoxia, Gao, Yue, Li, Xiaobai, Jarjoura, David, Byrd, John C., Johnson, Amy J., Phelps, Mitch A.
Format: Artigo
Sprog:Inglês
Udgivet: Springer US 2012
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3475844/
https://ncbi.nlm.nih.gov/pubmed/22956478
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12248-012-9401-2
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