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Cardiomyocytes from late embryos and neonates do optimal work and striate best on substrates with tissue-level elasticity: metrics and mathematics

In this review, we discuss recent studies on the mechanosensitive morphology and function of cardiomyocytes derived from embryos and neonates. For early cardiomyocytes cultured on substrates of various stiffnesses, contractile function as measured by force production, work output and calcium handlin...

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Библиографические подробности
Главные авторы: Majkut, Stephanie F., Discher, Dennis E.
Формат: Artigo
Язык:Inglês
Опубликовано: 2012
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3475743/
https://ncbi.nlm.nih.gov/pubmed/22752667
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10237-012-0413-8
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