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Severe stress switches CRF action in the nucleus accumbens from appetitive to aversive
Stressors motivate an array of adaptive responses ranging from “fight or flight” to an internal urgency signal facilitating long-term goals(1). However, traumatic or chronic uncontrollable stress promotes the onset of Major Depressive Disorder where acute stressors lose their motivational properties...
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Main Authors: | , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2012
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3475726/ https://ncbi.nlm.nih.gov/pubmed/22992525 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature11436 |
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