Stoichiometry of the Human Glycine Receptor Revealed by Direct Subunit Counting

The subunit stoichiometry of heteromeric glycine-gated channels determines fundamental properties of these key inhibitory neurotransmitter receptors; however, the ratio of α1- to β-subunits per receptor remains controversial. We used single-molecule imaging and stepwise photobleaching in Xenopus ooc...

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Autores principales: Durisic, Nela, Godin, Antoine G., Wever, Claudia M., Heyes, Colin D., Lakadamyali, Melike, Dent, Joseph A.
Formato: Artigo
Lenguaje:Inglês
Publicado: Society for Neuroscience 2012
Materias:
Brief Communications
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3475605/
https://ncbi.nlm.nih.gov/pubmed/22973015
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2050-12.2012
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