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The Genetics of Alzheimer Disease

Family history is the second strongest risk factor for Alzheimer disease (AD) following advanced age. Twin and family studies indicate that genetic factors are estimated to play a role in at least 80% of AD cases. The inheritance of AD exhibits a dichotomous pattern. On one hand, rare mutations in A...

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Библиографические подробности
Главный автор: Tanzi, Rudolph E.
Формат: Artigo
Язык:Inglês
Опубликовано: Cold Spring Harbor Laboratory Press 2012
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3475404/
https://ncbi.nlm.nih.gov/pubmed/23028126
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a006296
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