Amplification and Temporal Filtering during Gradient Sensing by Nerve Growth Cones Probed with a Microfluidic Assay

Nerve growth cones (GCs) are chemical sensors that convert graded extracellular cues into oriented axonal motion. To ensure a sensitive and robust response to directional signals in complex and dynamic chemical landscapes, GCs are presumably able to amplify and filter external information. How these...

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Main Authors: Morel, Mathieu, Shynkar, Vasyl, Galas, Jean-Christophe, Dupin, Isabelle, Bouzigues, Cedric, Studer, Vincent, Dahan, Maxime
Format: Artigo
Sprog:Inglês
Udgivet: The Biophysical Society 2012
Fag:
Cell Biophysics
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3475333/
https://ncbi.nlm.nih.gov/pubmed/23083707
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2012.08.040
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