Evidence for Transcriptional Factor Dysregulation in the Dorsal Raphe Nucleus of Patients with Major Depressive Disorder

Extensive evidence implicates dysfunction in serotonin (5-HT) signaling in the etiology of major depressive disorder (MDD). Dorsal raphe nucleus (DR) is a major source of serotonin in the brain, and previous studies have reported within it alterations in 5-HT-related gene expression, protein levels,...

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Main Authors:	Kerman, Ilan A., Bernard, René, Bunney, William E., Jones, Edward G., Schatzberg, Alan F., Myers, Richard M., Barchas, Jack D., Akil, Huda, Watson, Stanley J., Thompson, Robert C.
Format:	Artigo
Language:	Inglês
Published:	Frontiers Media S.A. 2012
Subjects:	Neuroscience
Online Access:	https://ncbi.nlm.nih.gov/pmc/articles/PMC3475304/ https://ncbi.nlm.nih.gov/pubmed/23087602 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnins.2012.00135
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Evidence for Transcriptional Factor Dysregulation in the Dorsal Raphe Nucleus of Patients with Major Depressive Disorder

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