Identification of Rat Rosa26 Locus Enables Generation of Knock-In Rat Lines Ubiquitously Expressing tdTomato

Recent discovery of a method for derivation and culture of germline-competent rat pluripotent stem cells (PSCs) enables generation of transgenic rats or knock-out rats via genetic modification of such PSCs. This opens the way to use rats, as is routine in mice, for analyses of gene functions or phys...

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Autors principals: Kobayashi, Toshihiro, Kato-Itoh, Megumi, Yamaguchi, Tomoyuki, Tamura, Chihiro, Sanbo, Makoto, Hirabayashi, Masumi, Nakauchi, Hiromitsu
Format: Artigo
Idioma:Inglês
Publicat: Mary Ann Liebert, Inc. 2012
Matèries:
Original Research Reports
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3475147/
https://ncbi.nlm.nih.gov/pubmed/22564063
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/scd.2012.0065
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