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CuAAC Click Chemistry Accelerates the Discovery of Novel Chemical Scaffolds as Promising Protein Tyrosine Phosphatases Inhibitors

Protein tyrosine phosphatases (PTPs) are crucial regulators for numerous biological processes in nature. The dysfunction and overexpression of many PTP members have been demonstrated to cause fatal human diseases such as cancers, diabetes, obesity, neurodegenerative diseases and autoimmune disorders...

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Detalhes bibliográficos
Main Authors: He, X.-P., Xie, J., Tang, Y., Li, J., Chen, G.-R.
Formato: Artigo
Idioma:Inglês
Publicado em: Bentham Science Publishers 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3474962/
https://ncbi.nlm.nih.gov/pubmed/22455590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2174/092986712800269245
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