Dimerization and direct membrane interaction of Nup53 contribute to nuclear pore complex assembly

Nuclear pore complexes (NPCs) fuse the two membranes of the nuclear envelope (NE) to a pore, connecting cytoplasm and nucleoplasm and allowing exchange of macromolecules between these compartments. Most NPC proteins do not contain integral membrane domains and thus it is largely unclear how NPCs are...

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Détails bibliographiques
Auteurs principaux: Vollmer, Benjamin, Schooley, Allana, Sachdev, Ruchika, Eisenhardt, Nathalie, Schneider, Anna M, Sieverding, Cornelia, Madlung, Johannes, Gerken, Uwe, Macek, Boris, Antonin, Wolfram
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2012
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3474928/
https://ncbi.nlm.nih.gov/pubmed/22960634
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2012.256
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