Alternative 3′-end processing of long noncoding RNA initiates construction of nuclear paraspeckles

Paraspeckles are unique subnuclear structures built around a specific long noncoding RNA, NEAT1, which is comprised of two isoforms produced by alternative 3′-end processing (NEAT1_1 and NEAT1_2). To address the precise molecular processes that lead to paraspeckle formation, we identified 35 paraspe...

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Autors principals: Naganuma, Takao, Nakagawa, Shinichi, Tanigawa, Akie, Sasaki, Yasnory F, Goshima, Naoki, Hirose, Tetsuro
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2012
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3474925/
https://ncbi.nlm.nih.gov/pubmed/22960638
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2012.251
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