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Mechanical Stretch Modulates MicroRNA 21 Expression, Participating in Proliferation and Apoptosis in Cultured Human Aortic Smooth Muscle Cells

OBJECTIVES: Stretch affects vascular smooth muscle cell proliferation and apoptosis, and several responsible genes have been proposed. We tested whether the expression of microRNA 21 (miR-21) is modulated by stretch and is involved in stretch-induced proliferation and apoptosis of human aortic smoot...

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Detalhes bibliográficos
Main Authors: Song, Jian tao, Hu, Bo, Qu, Hai yan, Bi, Cheng long, Huang, Xiao zhen, Zhang, Mei
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3474731/
https://ncbi.nlm.nih.gov/pubmed/23082189
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0047657
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