Nicotinamide Mononucleotide Adenylyltransferase 2 (Nmnat2) Regulates Axon Integrity in the Mouse Embryo

Using transposon-mediated gene-trap mutagenesis, we have generated a novel mouse mutant termed Blad (Bloated Bladder). Homozygous mutant mice die perinatally showing a greatly distended bladder, underdeveloped diaphragm and a reduction in total skeletal muscle mass. Wild type and heterozygote mice a...

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Détails bibliographiques
Auteurs principaux: Hicks, Amy N., Lorenzetti, Diego, Gilley, Jonathan, Lu, Baisong, Andersson, Karl-Erik, Miligan, Carol, Overbeek, Paul A., Oppenheim, Ronald, Bishop, Colin E.
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2012
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3474723/
https://ncbi.nlm.nih.gov/pubmed/23082226
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0047869
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