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The RanBP2/RanGAP1*SUMO1/Ubc9 complex: A multisubunit E3 ligase at the intersection of sumoylation and the RanGTPase cycle

Posttranslational modification of proteins with SUMO and the RanGTP/GDP cycle are two essential cellular mechanisms contributing directly or indirectly to almost every cellular event. The SUMO E3 ligase RanBP2 (Nup358) and the Ran GTPase activating protein (RanGAP1) are known to form a stable comple...

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Detalhes bibliográficos
Main Authors: Flotho, Annette, Werner, Andreas
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3474663/
https://ncbi.nlm.nih.gov/pubmed/22925898
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/nucl.21980
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