Clinical and Biomarker Changes in Dominantly Inherited Alzheimer’s Disease

BACKGROUND: The order and magnitude of pathologic processes in Alzheimer’s disease are not well understood, partly because the disease develops over many years. Autosomal dominant Alzheimer’s disease has a predictable age at onset and provides an opportunity to determine the sequence and magnitude o...

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Autores principales: Bateman, Randall J., Xiong, Chengjie, Benzinger, Tammie L.S., Fagan, Anne M., Goate, Alison, Fox, Nick C., Marcus, Daniel S., Cairns, Nigel J., Xie, Xianyun, Blazey, Tyler M., Holtzman, David M., Santacruz, Anna, Buckles, Virginia, Oliver, Angela, Moulder, Krista, Aisen, Paul S., Ghetti, Bernardino, Klunk, William E., McDade, Eric, Martins, Ralph N., Masters, Colin L., Mayeux, Richard, Ringman, John M., Rossor, Martin N., Schofield, Peter R., Sperling, Reisa A., Salloway, Stephen, Morris, John C.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2012
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3474597/
https://ncbi.nlm.nih.gov/pubmed/22784036
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1056/NEJMoa1202753
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