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Chemotherapy by intravenous administration of conjugates of daunomycin with monoclonal and conventional anti-rat alpha-fetoprotein antibodies.

Monoclonal antibodies to rat alpha-fetoprotein (AFP) were produced by hybridization of mouse myeloma cells with spleen cells from mice immunized with rat AFP. The monoclonal antibodies as well as horse anti-rat AFP were coupled via a dextran bridge to daunomycin. Both types of conjugates were tested...

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Détails bibliographiques
Publié dans:Proc Natl Acad Sci U S A
Auteurs principaux: Tsukada, Y, Hurwitz, E, Kashi, R, Sela, M, Hibi, N, Hara, A, Hirai, H
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 1982
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC347456/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6185954/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.79.24.7896
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