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Na+/H+ antiport in Swiss 3T3 cells: mitogenic stimulation leads to cytoplasmic alkalinization.

Addition of Na+ to Na+-depleted Swiss 3T3 cells causes a rapid and dramatic increase in intracellular pH, as monitored by uptake of the weak acid 5,5-dimethyloxazolidine-2,4-dione. The effect of Na+ is concentration dependent (half-maximal effect at 38 mM); this cation can be replaced by Li+ but not...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Principais autores: Schuldiner, S, Rozengurt, E
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 1982
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Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC347431/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6961450/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.79.24.7778
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