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Does Nrf2 Contribute to p53-Mediated Control of Cell Survival and Death?
In response to oxidative stress, the transcription factor Nrf2 is upregulated and controls activation of many genes that work in concert to defend cells from damages and to maintain cellular redox homeostasis. p53 has been regarded as the guardian of the genome through its pro-oxidant and antioxidan...
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| Autori principali: | , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Mary Ann Liebert, Inc.
2012
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3474188/ https://ncbi.nlm.nih.gov/pubmed/22559194 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/ars.2012.4674 |
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