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Protein-Thiol Oxidation and Cell Death: Regulatory Role of Glutaredoxins

Significance: Glutaredoxin (Grx) is the primary enzyme responsible for catalysis of deglutathionylation of protein-mixed disulfides with glutathione (GSH) (protein-SSG). This reversible post-translational modification alters the activity and function of many proteins important in regulation of criti...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Allen, Erin M.G., Mieyal, John J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Mary Ann Liebert, Inc. 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3474186/
https://ncbi.nlm.nih.gov/pubmed/22530666
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/ars.2012.4644
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