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Preparation of brain membranes containing a single type of opioid receptor highly selective for dynorphin.
Opioid receptors on guinea pig brain membranes were alkylated by the naltrexone analogue beta-chlornaltrexamine. Binding of the prototypical mu and kappa ligands, [3H]dihydromorphine and [3H]ethylketocyclazocine, was more readily affected by the reagent than was binding of the delta ligand, 3H-label...
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| Publicado no: | Proc Natl Acad Sci U S A |
|---|---|
| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1982
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC347382/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6130527/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.79.23.7570 |
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