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Mutant immunoglobulin genes have repetitive DNA elements inserted into their intervening sequences.

The kappa light chain genes from two mutant hybridoma cell lines defective in kappa light chain synthesis were isolated and compared to the wild-type kappa light chain gene. In each case, the mutant kappa light chain genes were found to contain repetitive DNA elements in their intervening sequences...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Main Authors: Hawley, R G, Shulman, M J, Murialdo, H, Gibson, D M, Hozumi, N
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 1982
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Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC347352/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6296832/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.79.23.7425
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