Inhibition of Opioid Transmission at the μ-Opioid Receptor Prevents Both Food Seeking and Binge-Like Eating

Endogenous opioids, and in particular μ-opioid receptors, have been linked to hedonic and rewarding mechanisms engaged during palatable food intake. The aim of this study was to investigate the effects of GSK1521498, a novel μ-opioid receptor antagonist, on food-seeking behavior and on binge-like ea...

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Detalhes bibliográficos
Main Authors: Giuliano, Chiara, Robbins, Trevor W, Nathan, Pradeep J, Bullmore, Edward T, Everitt, Barry J
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2012
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3473330/
https://ncbi.nlm.nih.gov/pubmed/22805601
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2012.128
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