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Gonadotropin-releasing hormone stimulation of luteinizing hormone release: A ligand-receptor-effector model.

A divalent antibody conjugate of a pure antagonist of gonadotropin-releasing hormone (GnRH) behaved as an agonist--i.e., released luteinizing hormone (LH) from pituitary cultures. Release was measured over a wide range of conjugate concentrations; it rose to a maximum of 66% of the LH released by th...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Blum, J J, Conn, P M
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1982
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC347328/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6296828/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.79.23.7307
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