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Ultrastructural basis for chloroquine-induced increase in intracellular insulin in adipocytes: alteration of lysosomal function.

A quantitative morphological analysis of insulin uptake into adipocytes was undertaken to determine the structural basis for chloroquine-induced increases in intracellular insulin. Adipocytes were incubated with ferritin-labeled insulin in the presence or absence of 50 microM chloroquine at 37 degre...

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Bibliografiske detaljer
Udgivet i:Proc Natl Acad Sci U S A
Main Authors: Smith, R M, Jarett, L
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1982
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC347327/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6760194/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.79.23.7302
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