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Bone morphogenetic proteins regulate hinge point formation during neural tube closure by dynamic modulation of apicobasal polarity

BACKGROUND: A critical event in neural tube closure is the formation of median (MHP) and dorsolateral hinge points (DLHP). Together, they buckle the ventral midline, elevate and juxtapose the neural folds for proper neural tube closure. Dynamic cell behaviors occur at hinge points (HPs), but their m...

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Detalles Bibliográficos
Main Authors: Eom, Dae Seok, Amarnath, Smita, Fogel, Jennifer L., Agarwala, Seema
Formato: Artigo
Idioma:Inglês
Publicado: 2012
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3473165/
https://ncbi.nlm.nih.gov/pubmed/22865775
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bdra.23052
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