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NOS2 enhances KRAS-induced lung carcinogenesis, inflammation and microRNA-21 expression
Mutant KRAS in lung cancers induce molecular pathways that regulate cellular proliferation, survival and inflammation, which enhance tumorigenesis. Inducible nitric oxide synthese (NOS2) up-regulation and sustained nitric oxide (NO•) generation are induced during the inflammatory response and correl...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3473150/ https://ncbi.nlm.nih.gov/pubmed/22618808 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.27644 |
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