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Reliable Single Chip Genotyping with Semi-Parametric Log-Concave Mixtures

The common approach to SNP genotyping is to use (model-based) clustering per individual SNP, on a set of arrays. Genotyping all SNPs on a single array is much more attractive, in terms of flexibility, stability and applicability, when developing new chips. A new semi-parametric method, named SCALA,...

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Autors principals: Rippe, Ralph C. A., Meulman, Jacqueline J., Eilers, Paul H. C.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3473070/
https://ncbi.nlm.nih.gov/pubmed/23077503
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0046267
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