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Altered Nucleotide-Microtubule Coupling and Increased Mechanical Output by a Kinesin Mutant

Kinesin motors hydrolyze ATP to produce force and do work in the cell – how the motors do this is not fully understood, but is thought to depend on the coupling of ATP hydrolysis to microtubule binding by the motor. Transmittal of conformational changes from the microtubule- to the nucleotide-bindin...

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Hlavní autoři: Liu, Hong-Lei, Hallen, Mark A., Endow, Sharyn A.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3473065/
https://ncbi.nlm.nih.gov/pubmed/23077560
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0047148
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