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Prion Domain of Yeast Ure2 Protein Adopts a Completely Disordered Structure: A Solid-Support EPR Study

Amyloid fibril formation is associated with a range of neurodegenerative diseases in humans, including Alzheimer’s, Parkinson’s, and prion diseases. In yeast, amyloid underlies several non-Mendelian phenotypes referred to as yeast prions. Mechanism of amyloid formation is critical for a complete und...

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Autors principals: Ngo, Sam, Chiang, Vicky, Ho, Elaine, Le, Linh, Guo, Zhefeng
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3473064/
https://ncbi.nlm.nih.gov/pubmed/23077577
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0047248
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