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Methylation of p15(INK4b) and Expression of ANRIL on Chromosome 9p21 Are Associated with Coronary Artery Disease

BACKGROUND: Genome-wide association studies have identified that multiple single nucleiotide polymorphisms on chromosome 9p21 are tightly associated with coronary artery disease (CAD). However, the mechanism linking this risk locus to CAD remains unclear. METHODOLOGY/PRINCIPAL FINDINGS: The methylat...

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Detalhes bibliográficos
Main Authors: Zhuang, Jianhui, Peng, Wenhui, Li, Hailing, Wang, Wei, Wei, Yidong, Li, Weiming, Xu, Yawei
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3473029/
https://ncbi.nlm.nih.gov/pubmed/23091611
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0047193
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