Plasma-Derived Exosomal Survivin, a Plausible Biomarker for Early Detection of Prostate Cancer

BACKGROUND: Survivin is expressed in prostate cancer (PCa), and its downregulation sensitizes PCa cells to chemotherapeutic agents in vitro and in vivo. Small membrane-bound vesicles called exosomes, secreted from the endosomal membrane compartment, contain RNA and protein that they readily transpor...

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Detalhes bibliográficos
Main Authors: Khan, Salma, Jutzy, Jessica M. S., Valenzuela, Malyn May A., Turay, David, Aspe, Jonathan R., Ashok, Arjun, Mirshahidi, Saied, Mercola, Dan, Lilly, Michael B., Wall, Nathan R.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3473028/
https://ncbi.nlm.nih.gov/pubmed/23091600
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0046737
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