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Studies on the Interactions of Copper and Zinc Ions with β-Amyloid Peptides by a Surface Plasmon Resonance Biosensor

The aggregation of β-amyloid peptide (Aβ) into fibrils plays an important role in the pathogenesis of Alzheimer’s disease (AD). Metal ions including copper and zinc are closely connected to the precipitation and toxicity of Aβ. In this study, a surface plasmon resonance (SPR) biosensor was construct...

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Detalhes bibliográficos
Main Authors: Yao, Fujun, Zhang, Ruiping, Tian, He, Li, Xiangjun
Formato: Artigo
Idioma:Inglês
Publicado em: Molecular Diversity Preservation International (MDPI) 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3472777/
https://ncbi.nlm.nih.gov/pubmed/23109885
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms130911832
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