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Asymmetric Dimethylarginine, Endothelial Dysfunction and Renal Disease

l-Arginine (Arg) is oxidized to l-citrulline and nitric oxide (NO) by the action of endothelial nitric oxide synthase (NOS). In contrast, protein-incorporated Arg residues can be methylated with subsequent proteolysis giving rise to methylarginine compounds, such as asymmetric dimethylarginine (ADMA...

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Detalhes bibliográficos
Main Authors: Aldámiz-Echevarría, Luis, Andrade, Fernando
Formato: Artigo
Idioma:Inglês
Publicado em: Molecular Diversity Preservation International (MDPI) 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3472745/
https://ncbi.nlm.nih.gov/pubmed/23109853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms130911288
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