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NAD(P)H:Quinone Oxidoreductase 1 (NQO1) P187S Polymorphism and Prostate Cancer Risk in Caucasians

NAD(P)H:quinone oxidoreductase 1 (NQO1) catalyses the reduction of quinoid compounds to hydroquinones, preventing the generation of free radicals and reactive oxygen. A “C” to “T” transversion at position 609 of NQO1, leading to a nonsynonymous amino acid change (Pro187Ser, P187S), results in an alt...

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Detalhes bibliográficos
Main Authors: Stoehr, Christine G., Nolte, Elke, Wach, Sven, Wieland, Wolf F., Hofstaedter, Ferdinand, Hartmann, Arndt, Stoehr, Robert
Formato: Artigo
Idioma:Inglês
Publicado em: Molecular Diversity Preservation International (MDPI) 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3472723/
https://ncbi.nlm.nih.gov/pubmed/23109831
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms130910959
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