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A model of spatially restricted transcription in opposing gradients of activators and repressors

Morphogens control patterns of transcription in development, often by establishing concentration gradients of a single transcriptional activator. However, many morphogens, including Hedgehog, create opposing activator and repressor gradients (OARGs). In contrast to single activator gradients, it is...

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Detalhes bibliográficos
Main Authors: White, Michael A, Parker, Davis S, Barolo, Scott, Cohen, Barak A
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3472688/
https://ncbi.nlm.nih.gov/pubmed/23010997
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/msb.2012.48
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