The inoculum effect and band-pass bacterial response to periodic antibiotic treatment

The inoculum effect (IE) refers to the decreasing efficacy of an antibiotic with increasing bacterial density. It represents a unique strategy of antibiotic tolerance and it can complicate design of effective antibiotic treatment of bacterial infections. To gain insight into this phenomenon, we have...

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Bibliographic Details
Main Authors: Tan, Cheemeng, Phillip Smith, Robert, Srimani, Jaydeep K, Riccione, Katherine A, Prasada, Sameer, Kuehn, Meta, You, Lingchong
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2012
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3472685/
https://ncbi.nlm.nih.gov/pubmed/23047527
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/msb.2012.49
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